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Synthetic Studies toward the C14–C29 Fragment of Mirabalin

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NIAID Data Ecosystem2026-03-09 收录
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A convergent synthesis of one isomer of the C14–C29 fragment of mirabalin is disclosed. The key steps include a Marshall allenylation, a Mukaiyama aldol reaction and a Crimmins aldolization, which allow the control of 10 out of 25 stereogenic centers present in the molecule.

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2016-09-12
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