HDAC enzyme activity for ACY-1083, Ricolinostat and Tubastatin A.

NIAID Data Ecosystem2026-03-14 收录

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https://figshare.com/articles/dataset/HDAC_enzyme_activity_for_ACY-1083_Ricolinostat_and_Tubastatin_A_/21319666 数据链接链接失效反馈

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HDAC enzyme activity for ACY-1083, Ricolinostat and Tubastatin A.

创建时间：

2022-10-12

miRNA expression of lymphoma cell lines with or without HDAC inhibitor treatment

淋巴瘤miRNA表达

HDAC抑制剂

Various types of HDAC inhibitor are now planned or on going to use against non-Hodgkin’s lymphoma including CTCL. However there is a lack of molecular based evidence not only for which HDACi might be

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Extending Cross Metathesis To Identify Selective HDAC Inhibitors: Synthesis, Biological Activities, and Modeling

HDAC抑制剂

癌症靶向治疗

Dissymmetric cross metathesis of alkenes as a convergent and general synthetic strategy allowed for the preparation of a new small series of human histone deacetylases (HDAC) inhibitors. Alkenes beari

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Hydrazide-Based Class I Selective HDAC Inhibitors Completely Reverse Chemoresistance Synergistically in Platinum-Resistant Solid Cancer Cells

癌症耐药性

HDAC抑制剂

In this work, we have synthesized a set of peptoid-based histone deacetylase inhibitors (HDACi) with a substituted hydrazide moiety as zinc-binding group. Subsequently, all compounds were evaluated in

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Computational Exploration of Zinc Binding Groups for HDAC Inhibition

HDAC抑制剂

计算化学药物筛选

Histone deacetylases (HDACs) have emerged as important drug targets in epigenetics. The most common HDAC inhibitors use hydroxamic acids as zinc binding groups despite unfavorable pharmacokinetic prop

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Receptor-independent ectopic activity of PROLACTIN predicts aggressive lung tumors and indicates HDACi-based therapeutic strategies

癌症分子机制

HDAC抑制剂

Aim: PROLACTIN (PRL), normally produced by the pituitary gland, acts through its receptor (PRL-R) to initiate a signalling cascade to the genome. PRL can also be produced by cancer cells and become on

NIAID Data Ecosystem20

HDAC enzyme activity for ACY-1083, Ricolinostat and Tubastatin A.

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