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Quinoidal Tetrazines: Formation of a Fascinating Compound Class

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NIAID Data Ecosystem2026-03-06 收录
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A series of different N-heterocyclic carbenes (NHCs) were reacted with 3,6-bis(3‘,5‘-dimethylpyrazolyl)-tetrazine in the presence of an inorganic carbonate to provide access to a hitherto unprecedented compound class. The formed tetrazine derivatives bearing the NHC in the 3-position and an oxygen in the 6-position show a quinoidal-like structure, according to physical examinations and X-ray crystallography.

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2016-06-03
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