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Crystal structure of the Retinoic Acid Receptor alpha in complex with a synthetic spiroketal agonist and a fragment of the TIF2 co-activator.

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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Crystal structure of the Retinoic Acid Receptor alpha in complex with a synthetic spiroketal agonist and a fragment of the TIF2 co-activator. Descriptor: (2~{R})-6,6,9,9-tetramethylspiro[3,4,7,8-tetrahydrobenzo[g]chromene-2,2'-3,4-dihydrochromene]-6'-carboxylic acid, HIS-LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN-ASP, Retinoic acid receptor RXR-alpha Authors: Andrei, S.A, Ottmann, C. Deposit date: 2016-09-28 Release date: 2017-04-26 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.17 Å) Cite: Designed Spiroketal Protein Modulation. Angew. Chem. Int. Ed. Engl., 56, 2017

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2016-09-28
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