High-throughput determination of let-7a and miR-21 loaded RISC cleavage kinetics
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下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP175010
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资源简介：
Argonaute proteins loaded with small interfering RNAs (siRNAs) or microRNAs (miRNA) form the RNA-Induced Silencing Complex (RISC), which represses target RNA expression. We applied high-throughput methods to measure single-turnover cleavage rates of RISC in vitro and to measure knockdown of thousands of RISC targets in an engineered cellular system.
创建时间：
2019-07-16
