IL-3 receptor signaling suppresses chronic intestinal inflammation by controlling mechanobiology and tissue egress of regulatory T cells

We studied the impact of Il3r deficiency on freshly isolated thymocytes of steady-state IL3R alpha deficient and wildtype mice. RNA-sequencing of murine steady-state Interleukin-3 (IL-3) receptor alpha deficient (Il3ra-/-) and wildtype (Il3ra+/+) thymocytes of 3 mice per group.本研究探究了白细胞介素3受体（Interleukin-3 Receptor, IL-3R）缺陷对稳态条件下野生型与IL-3Rα缺陷型小鼠新鲜分离胸腺细胞的影响。本研究对每组各3只小鼠的白细胞介素3（IL-3）受体α链缺陷型（Il3ra-/-）与野生型（Il3ra+/+）胸腺细胞开展了RNA测序（RNA-sequencing）。