Embryos derived from the transgenic line of Tg(cmlc2::GFP) were used, and the cardiac morphology was observed by fluorescence microscope. The major cardiac phenotype of Nkx2.5/2.7-MO morphants reveale
Aneurysm and dissection of the aortic root is a common cause of morbidity and mortality in Loeys-Dietz Syndrome (LDS) and Marfan Syndrome (MFS), where perturbations in TGF β signaling play a causa
