Data for "NKG2A-mediated immune modulation of natural killer cells by <i>Staphylococcus aureus</i>"

The datafile contains raw data for each Figure or supplemental figure in the paper with graphical datasets. A brief description for each figure is given below: - Figure 1 - Data demonstrating that CD57- NKG2A+ natural killer (NK) cells expand in vivo during Staphylococcus aureus bacteremia in humans Figure 2 - Data demonstrating that patients with Staphylococcus aureus bacteremia display increased frequencies of NKp30− Siglec-7− NK cells. Figure 3 - Data demonstrating that TSST-1 promotes the expansion of CD57− NKG2A+ NK cells. Figure 4 - Data demonstrating that TSST-1–mediated alterations in NKG2A+ NK cells are more pronounced over time Figure 5 - Data demonstrating that TSST-1–mediated polarization toward a CD57− NKG2A+ NK cell phenotype involves an IL-12–independent mechanism. Figure 6 - Data demonstrating that CD56dim NK cells in human patients with Staphylococcus aureus bacteremia are more polyfunctional Figure S2 - Data demonstrating NK cell frequencies in healthy controls and patients hospitalized with Staphylococcus aureus bacteremia Figure S3 - Data demonstrating phenotypic analyses of CD56+ T cells in healthy controls and patients hospitalized with Staphylococcus aureus bacteremia Figure S4 - Data demonstrating that plasma IL-12p70 levels are not reduced in patients with Staphylococcus aureus bacteremia Figure S5 - Data demonstrating that CD57− NKG2A+ or NKp30− Siglec-7− NK cells do not increase in frequency in vivo during Escherichia coli bacteremia in humans Figure S6 - Data demonstrating that CD56 positivity in NK cells and T cells dictate hyperresponsiveness to superantigens Figure S7 - Data demonstrating phenotypic analyses of CD56dim and CD56hi NK cells following super antigen stimulation Figure S8 - Data demonstrating that IFN-gamma production in response to superantigen stimulation is mostly confined to CD57− NKG2C− NKG2A+ NK cell subsets Figure S9 - Data demonstrating the percentage of IFN-gamma+ CD56dim NK cells elicited after TSST-1 stimulation following IL-12 blockade