Data Files, Chronotherapy

Title: Data Files, ChronotherapyResearch genre: DataCreator: Axelrod, David E.Date created: 2020Extent: 6 Excel files, each 11 KB Intended Audience: ScienceDescription: Output of chronotherapy simulated with NetLogo computer program Colon_Crypt_Model_073120.nlogo created in NetLogo version 5.3.1. The model was revised and renamed Colon_Crypt_Model_041321.nlogo in order to run with NetLogo version 6.2.0. The model is described in a separate file. Each data file is the result of cytotoxic chemotherapy during a different 4-hour period during the day. The file names indicate the time period (Phase) that chemotherapy was active. Data in each column include the following, A: run number, with the number of time steps when mutants were initiated and the number of time steps that chemotherapy was initiated; B: whether or not the mutants overflowed the crypt and the mutants were not eliminated from the crypt (cured); C: the time step at which the mutants were eliminated from the crypt (cured); D: time steps between the time that chemotherapy was on and the time that mutants were cured; E: time to cure mutants in hours, assuming one time step equals four hours.; F: time to cure mutants in days; G: time of day, in hours, when chemotherapy was initiated. A forthcoming publication will describe the computer program and simulation results of circadian-timed chemotherapy.Research Domain: ScienceRights statement: The author owns the copyright to this work