Transcriptome analysis among senescent cells induced by various stimuli. Transcriptome analysis among senescent cells induced by various stimuli

We carried out the analysis using human skin fibrobllast HCA2 (MJ90) cells. Cells were indcued to be senescent cells by treatment with doxorubicin for 24 hrs, tert-butyl-hydroperoxide for 24 hrs, or serial passages as well as nultin3a + RO3306. As a result, we found simailar transcriptome signatures among senescent cells induced by various stimuli Overall design: Examination of young and 4 types of senescent HCA2 cells induced by different stimuli.