Genes with differential importance in iron utilization by Mycobacterium tuberculosis.

45 genes selected from the 165 varying genes which were assessed by HMM analysis as either essential (ES), “essential domain” (ESD) or “growth defect” (GD) under different iron conditions. The 21 genes which were classified as essential or “growth defect” under all iron conditions (S6 Table) were excluded from this list. cMBT: carboxymycobactin, MBT: mycobactin at high or low concentrations, hemin (Hm), hemoglobin (Hb) and hemin plus mycobactin (Hm/MBT). NE: non-essential.