官方服务：
资源简介：
5- AZA treatment of EWS cell lines
应用场景：
创建时间：
2012-09-01
相关数据集
Simple oligonucleotide-based multiplexing of single-cell chromatin accessibility. Simple oligonucleotide-based multiplexing of single-cell chromatin accessibility
we reported the development of an accurate, easy-to-use and scalable system (SNuBar) for multiplexing single cell ATAC or multi-omics (ATAC&RNA) assays, and applied this method to multiplex therapy co
NIAID Data Ecosystem50
Inhibiting EZH2 Targets Atypical Teratoid Rhabdoid Tumor by Triggering Viral Mimicry via Both RNA and DNA Sensing Pathways [CUT&RUN]. Inhibiting EZH2 Targets Atypical Teratoid Rhabdoid Tumor by Triggering Viral Mimicry via Both RNA and DNA Sensing Pathways [CUT&RUN]
Loss of function mutations in SMARCB1 are prevalent in pediatric atypical teratoid rhabdoid tumors (ATRTs) and confer an oncogenic dependency on EZH2, providing a compelling rationale for treating the
NIAID Data Ecosystem30
Supplementary Tables from Activation of a Subset of Evolutionarily Young Transposable Elements and Innate Immunity Are Linked to Clinical Responses to 5-Azacytidine
4 supplementary tables include information about patient characteristics (table S1), primer design (table S2), list of up-regulated genes (table S3), and list of gene ontology terms of the up-regulate
NIAID Data Ecosystem20
Targeting EZH2 and HDACs in hematological cancers induces transcriptional and metabolic deregulation causing ferroptosis
The methyltransferase EZH2 functions as the enzymatic component of the PRC2 complex, which deposits methyl groups on H3K27, leading to chromatin condensation and gene repression. Recent studies have s
NIAID Data Ecosystem30
Discovery and Characterization of Second-Generation BET Bromodomain Inhibitor RG6146. Discovery and Characterization of Second-Generation BET Bromodomain Inhibitor RG6146
BET Bromodomain inhibition is an epigenetic therapy that is being assessed as an anti-cancer strategy. Herein, we report the structure and activity of RG6146, a novel second-generation clinical grade
NIAID Data Ecosystem30
