Contribution of WT cells to the leading cell position when mixed 1:1 (50%: 50%) with another type of cell (equivalent WT or specified mutant).

Since as an initial setup of simulations we considered a sprout of width 2 (two voxels), there are two equivalent leading positions (Position 1 and Position 2) (outlined on each plot by cyan lines in Fig 12). The results are reported as mean value ± standard deviation for samples obtained from 100 realizations for each experimental scenario. Numerical setup is as specified in Fig 12.