Cartilage-anchored downregulation of circadian clock transcription factors in osteoarthritis: a meta-analysis with a powered informative null

Archived data and code accompanying the manuscript "Cartilage-anchored downregulation of circadian clock transcription factors in osteoarthritis: a meta-analysis with a powered informative null". The deposit contains the frozen analysis code, processed result tables (differential expression, ssGSEA scores, robust rank aggregation, WGCNA modules, MuSiC deconvolution, ligand-receptor permutation, single-cell pseudobulk, transcription-factor target enrichment), source data underlying the main figure panels, and the curated 227-gene circadian gene set with its source provenance. No raw sequencing data are included; all raw data accessions (GSE114007, GSE293276, GSE283079, GSE220243, GSE216651, GSE117999, E-MTAB-12184) are listed in the accompanying README.