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Tolerance to cocaine-induced motor effects in rats: transcriptomic regulations in the dorsal striatum

Alliance of Genome Resources2026-08-01 收录

可卡因成瘾

背侧纹状体转录组

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https://www.ncbi.nlm.nih.gov/gds/?term=GSE134154 数据链接链接失效反馈

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资源简介：

Comparison of gene expression in the dorsal striatum of rats after chronic binge or acute binge cocaine injections or saline treatment

应用场景：

药物分析

可卡因成瘾

Abstract A descriptive, exploratory and retrospective study that analyzed medical records of the patients under treatment for crack use; prescriptions and medicines interactions were collected, and th

DataCite Commons2022-05-30 更新80

Supplementary Material for: Evidence of hypothalamic-pituitary-adrenal and -gonadal dysfunction in cocaine-addicted men

可卡因成瘾

内分泌失调

Introduction: Regular cocaine use has been associated with hormonal dysfunction including hypogonadism, which can lead to fatigue, reduced stamina, sexual dysfunction and impaired quality of life. How

DataCite Commons2024-01-12 更新60

Use of hybrid mouse diversity panel to map genetic pathways related to cocaine addiction

遗传学

可卡因成瘾

This project will chart with high-resolution the genetic pathways that give rise to defined clinical phenotypes related to cocaine addiction. We will utilize the power of the hybrid mouse diversity pa

NIAID Data Ecosystem50

Thymic involution caused by repeated cocaine administration includes apoptotic cell loss followed by ectopic adipogenesis. Thymic involution caused by repeated cocaine administration includes apoptotic cell loss followed by ectopic adipogenesis

可卡因成瘾

胸腺退化

To obtain insight into the changes in thymus caused by repeated cocaine administration, we performed transcriptome analysis. Total RNAs from the control and cocaine groups (day 7) were subjected to DN

NIAID Data Ecosystem70

D2R control of cocaine use

可卡因成瘾

神经调控

Self-administration of cocaine induces a histone acetyltransferase previously never associated with addiction, Kat5. This HAT is induced by the dopamine/acetylcholine control of striatal circuits in r

DataCite Commons2025-12-10 更新60

Tolerance to cocaine-induced motor effects in rats: transcriptomic regulations in the dorsal striatum

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