Case-control meta-analysis of cohort Ia and cohort IIb in a total of 712 SLE cases and 1131 controls.

a Uppsala, Stockholm, Lund, n = 567 cases, n = 512 controls.b Linköping, n = 145 cases, n = 619 controls.c WHO class III or IV on renal biopsy, according to the 1995 WHO classification system [2]. Biopsies available in 178 patients.d Glomerular filtration rate 2[22]. Data available for 225 patients.e Unadjusted combined p-value and OR calculated using Cochran-Mantel Haenszel chi-square test. P-values remaining significant after Bonferroni correction for 4 tested SNPs are in italic.f Adjusted p-value and OR from meta-analysis of logistic regression results including age and gender as covariates. Number of cases and controls; lupus nephritis, n = 229, proliferative nephritis, n = 111, severe renal insufficiency, n = 31, SLE, n = 711, controls, n = 960.