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Specificity and Topology of the Escherichia coli Xanthosine Permease, a Representative of the NHS Subfamily of the Major Facilitator Superfamily

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PubMed Central2026-05-16 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC99545/
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资源简介:
The specificity of XapB permease was compared with that of the known nucleoside transporters NupG and NupC. XapB-mediated xanthosine uptake is abolished by 2,4-dinitrophenol and exhibits saturation kinetics with an apparent K(m) of 136 μM. A 12-transmembrane-segment model was confirmed by translational fusions to alkaline phosphatase and the α fragment of β-galactosidase.
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American Society for Microbiology (ASM)
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