Comparision of transcriptomes between murine WT type 1 conventional DCs to XCR1-deficient type 1 conventional DCs

We sought to compare the overall transcriptomic differences between TLR stimulated WT and XCR1-deficient type 1 conventional DCs. In addition, we also wanted to investigate functional role of XCR1 signaling in WT type 1 conventional DCs by treating recombinant murine XCL1, a ligand of XCR1 to these cells as well Total 4 samples are analyzed (WT LPS treated, WT LPS & rXCL1 treated, XCR1 KO LPS treated, XCR1 KO LPS & rXCL1 treated)