Stringency comparison of the three algorithms used in microarray data analysis.

The number of differentially expressed genes in the final gene list of each contrast is listed, together with the output of differentially expressed genes determined by each algorithm (Cyber-T, LPE and EB (Rocke)). For each algorithm, the number of genes excluded in the final gene list was calculated by subtracting the final gene list output from the algorithm input, and the percentage of excluded genes was listed and highlighted. EB (Rocke) was more stringent than the other two algorithms in that: 1) it yielded the smallest number of differentially expressed genes in all contrasts except contrast 3; 2) it yielded the lowest percentage of excluded genes in all contrasts, with the exception of contrast 3.