BIOGRID CURATED DATA FOR PMT1 (Saccharomyces cerevisiae (S288c))

Protein-Protein, Genetic, and Chemical Interactions for PMT1 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: Protein O-mannosyltransferase of the ER membrane; transfers mannose from dolichyl phosphate-D-mannose to protein serine and threonine residues; 1 of 7 related proteins involved in O-glycosylation which is essential for cell wall rigidity; involved in ER quality control; amino terminus faces cytoplasm, carboxyl terminus faces ER lumen

由 BioGRID (https://thebiogrid.org) 精心整理的 PMT1（酿酒酵母 S288c）蛋白质-蛋白质、遗传学以及化学相互作用数据集；定义：内质网膜蛋白 O-甘露糖基转移酶；将甘露糖从多聚甘露糖磷酸-D-甘露糖转移到蛋白丝氨酸和苏氨酸残基上；O-糖基化过程中涉及的7种相关蛋白之一，该过程对于细胞壁的刚性至关重要；参与内质网质量控制；氨基端面向细胞质，羧基端面向内质网腔。