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Paneth cell trancriptome: effect of DEX on TNF induced inflammatory response

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE281876
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We aimed to investiagte the protective anti-inflammatory effect of glucocorticoids (dexamethsone, DEX) on paneth cells from mice treated with TNF. TNF treatment causes leaky gut syndrome and paneth cell disfunction. Using pre-treatment with DEX we aim to protect paneth cell against TNF effects 4 groups with 4 biological replicates each for a total of 16 samples: PBS+PB treated, DEX+PBS treated, PBS+TNF treated and DEX+TNF treated
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2025-02-26
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