Crystal structure of XIAP-BIR3 with ALP2 series SMAC mimetic ligand
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Crystal structure of XIAP-BIR3 with ALP2 series SMAC mimetic ligand Descriptor: E3 ubiquitin-protein ligase XIAP, N-{(5M)-5-(3,5-dimethyl-1H-pyrazol-4-yl)-6-[(1,3-thiazol-5-yl)ethynyl]pyridin-2-yl}-N~2~-methyl-L-alaninamide, ZINC ION Authors: Nguyen, S, Lucet, I, Roy, M.J. Deposit date: 2025-01-27 Release date: 2026-01-21 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Expanding the toolbox to develop IAP-based degraders of TEAD transcription factors. Commun Chem, 9, 2026
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2025-01-27
