Crystal structure of E. coli LpxH in complex with lipid X
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Crystal structure of E. coli LpxH in complex with lipid X Descriptor: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, MANGANESE (II) ION, UDP-2,3-diacylglucosamine hydrolase Authors: Sooriyaarachchi, S, Bergfors, T, Jones, T.A, Mowbray, S.L. Deposit date: 2023-09-14 Release date: 2024-04-17 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria. Proc.Natl.Acad.Sci.USA, 121, 2024
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2023-09-14
