Densities and 3D distributions of synapses using FIB/SEM imaging in the human neocortex (Temporal cortex, T2)

Synapses have been identified, segmented and quantified in the human neocortex (Temporal cortex, T2) with 3D electron microscopy (FIB-SEM). Layer III of the Temporal cortex (T2 or Brodmann’s area 21) has been studied. 5 cases have been used (AB1, AB2, AB3, H18 and H38) to achieve a total of 9 valid images stacks. Data obtained include the number of asymmetric and symmetric synapses, their sizes and their spatial distribution.