Dataset 5: IL-15 increases cross-reactive antibody responses to H3N2 viruses

(A) B cells from healthy donors were co-stimulated with CpG ODN 2006 inactivated A/Vic11 viruses and interleukin 15. Strain-specific and HA stalk-reactive IgG in supernatants of activated B cells were detected after 6 days. (B) Fold change in cross-reactive antibodies. (B) Correlation between influenza specific antibodies and HA antigenic sequence. No correlation between cross-reactive antibodies and HA sequence was detected.