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Enoyl reductase-like; Leishmania infantum (strain JPCM5)
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Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases.
Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases.
NIAID Data Ecosystem50
Genes we prioritised as drug targets that had MR and colocalization evidence with other indications.
Gene expression-disease relationship identified in the main MR (instrument-gene-indication): Alzheimer’s disease (AD), Schizophrenia (Sz), anorexia (AN), suggested direction of drug action according t
Figshare2021-01-08 更新00
Factors of metronidazole resistance in the human parasite Trichomonas vaginalis
Trichomonas vaginalis is a sexually transmitted human parasite causing trichomoniasis, leading to vaginitis or cervicitis in many patients. Furthermore, infections can lead to premature labour or loss
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Global profiling of cancer cell recovery from therapy-induced stress reveals druggable vulnerabilities
Cancer cells survive therapy-induced stress, but how they resolve it is not clear. Using an integrated systems level approach we delineate the global mechanisms of cellular recovery from proteotoxic s
NIAID Data Ecosystem50
