<p>Compounds used to validate the cytochrome b signature. NMT: N-myristoyltransferase, PTR: pteridine reductase, DHFR-TS: dihydrofolate reductase-thymidylate synthase, NTR: nitroreductase, OSC: oxidosqualene cyclase, KRS: lysyl-tRNA synthetase, MRS: methionyl-tRNA synthetase, CPSF: cleavage and polyadenylation specificity factor. Note that NTR1 and NTR2 are not targets of nitroheterocyclic drugs but, rather, reductively activate the nitroheterocyclic prodrugs stated.</p>
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Compounds used to validate the cytochrome b signature. NMT: N-myristoyltransferase, PTR: pteridine reductase, DHFR-TS: dihydrofolate reductase-thymidylate synthase, NTR: nitroreductase, OSC: oxidosqualene cyclase, KRS: lysyl-tRNA synthetase, MRS: methionyl-tRNA synthetase, CPSF: cleavage and polyadenylation specificity factor. Note that NTR1 and NTR2 are not targets of nitroheterocyclic drugs but, rather, reductively activate the nitroheterocyclic prodrugs stated.
创建时间：
2026-01-20
