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Identification and biological evaluation of thiazole-based inverse agonists of RORgt

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Protein Data Bank Japan2024-03-13 更新2026-03-21 收录
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Identification and biological evaluation of thiazole-based inverse agonists of RORgt Descriptor: Nuclear receptor ROR-gamma, trans-3-({4-(cyclohexylmethyl)-5-[3-(1-methylcyclopropyl)-5-{[(2R)-1,1,1-trifluoropropan-2-yl]carbamoyl}phenyl]-1,3-thiazole-2-carbonyl}amino)cyclobutane-1-carboxylic acid Authors: Spurlino, J, Milligan, C. Deposit date: 2018-03-28 Release date: 2018-04-25 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Identification and biological evaluation of thiazole-based inverse agonists of ROR gamma t. Bioorg. Med. Chem. Lett., 28, 2018

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2018-03-28
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