Effects of <i>NR1I2</i> haplotype and <i>CYP2B6</i> genotypes on SF -mediated metabolic induction of bupropion hydroxylation.

*p<0.01, paired t test between the basal and induced states. ap<0.05, Wilcoxon rank-sum test for the NR1I2 groups within each CYP2B6 genotype group. bp<0.05, Wilcoxon rank-sum test for the CYP2B6 groups with TGT noncarriers. cp<0.05, Wilcoxon rank-sum test for the CYP2B6 groups with TGT carriers. dWilcoxon rank-sum test for the CYP2B6 groups; p<0.05 is indicated in bold. e% difference represents the percent difference between basal and induced state, calculated as an absolute of 100×(induced-basal)/basal.