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Increasing complexity of the dystrophin-associated protein complex.

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PubMed Central1994-08-30 更新2026-05-16 收录
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Duchenne muscular dystrophy is a severe X chromosome-linked, muscle-wasting disease caused by lack of the protein dystrophin. The exact function of dystrophin remains to be determined. However, analysis of its interaction with a large oligomeric protein complex at the sarcolemma and the identification of a structurally related protein, utrophin, is leading to the characterization of candidate genes for other neuromuscular disorders. IMAGES:

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1994-08-30
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