Genome wide CRISPR screen in AML chemotherapy resistance.
收藏NIAID Data Ecosystem2026-05-01 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP445590
下载链接
链接失效反馈官方服务：
资源简介：
Chemoresistance is the leading cause of acute myeloid leukemia (AML)-related deaths, and elucidation of the mechanisms of AML chemoresistance is necessary to effectively target this process. Here, we performed genome wide CRISPR-Cas9 screening to identify key molecules regulating AML chemoresistance. Overall design: sgRNA counts from THP-1 hCas9 cells infected with two lentiviral gRNA libraries challenged with IDA treatment (1.5 ng/mL) or kept in regular medium.
创建时间：
2023-09-13
