Mutation tables

We studied mutation accumulation in two potato clones, Desiree and Red Polenta, using layer enrichment and isolation by single cell regeneration. Our results indicate that mutations partition into two compartments, the L1 and the L2,3 and accumulate at 1.6-4.5X higher rates in the L1. Compared to stem cells, differentiated cells display mutation signatures consistent with the action of reactive oxygen species. Genic DNA, however, appears protected in all tested cell types.