Characteristics of studies of patients with BRCA1/2 mutated ovarian cancer.
收藏资源简介:
Histology: pathological histology of ovarian cancer, se = serous ovarian cancer, CCC = clear cell cancer of, Mu = mucinous ovarian cancer. all = almost all of the epithelial ovarian cancer types, including serous, mucinous, clear cell cancer, etc.Laboratory methods: laboratory methods used to detect BRCA1/2 mutation, PTT = Protein truncation test, SSCP = Single-Strand Conformation Polymorphism, seq = sequencing, DGGE = fluorescent multiplex denaturing gradient gel electrophoresis, MLPA = multiplex ligation-dependent probe amplification, DHPLC = Denaturing high performance liquid chromatography, RFLP = Restriction fragment length polymorphisms, F-CSGE = Fluorescence-based Conformation Sensitive Gel Electrophoresis.Germline/somatic: Germ = germline mutation, Mixed = BRCA1 germline/somatic mutation or BRCA1 promoter methylation.Mutation types: VUS = variants of unknown significance.Treatment: chemotherapy used, 1 = only Platinum was used, 2 = Platinum-based chemotherapy, 3 = other agents without Platinum, like Paclitaxel, etc.



