Catalytic fragment of masp-1 in complex with its specific inhibitor developed by directed evolution on sgci scaffold
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Catalytic fragment of masp-1 in complex with its specific inhibitor developed by directed evolution on sgci scaffold Descriptor: Mannan-binding lectin serine protease 1 heavy chain, Mannan-binding lectin serine protease 1 light chain, Protease inhibitor SGPI-2 Authors: Heja, D, Harmat, V, Fodor, K, Wilmanns, M, Dobo, J, Kekesi, K.A, Zavodszky, P, Gal, P, Pal, G. Deposit date: 2012-02-03 Release date: 2012-04-25 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2. J.Biol.Chem., 287, 2012
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2012-02-03
