The effect of GRK2 co-expression on the affinity of µ-opioid receptor ligands.
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Affinity for the low affinity site (KL) values were determined in competition binding assays versus [3H]diprenorphine in the presence of sodium ions and GTP, as described in the experimental section. Values are mean±s.e.m of three independent experiments. Affinity for the high affinity site (KH) values were determined in competition binding assays versus [3H]DAMGO in the presence of sodium ions, as described in the experimental section. Values are mean±s.e.m of four independent experiments.AValues are significantly different from those determined in the absence of GRK2 (p
创建时间：
2015-12-02
