Indole Alkaloids with New Skeleton Activating Neural Stem Cells
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https://figshare.com/articles/dataset/Indole_Alkaloids_with_New_Skeleton_Activating_Neural_Stem_Cells/2238220
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资源简介：
Alstoscholarisines A–E (1–5), five unprecedented monoterpenoid
indole alkaloids with 6/5/6/6/6
fused-bridge rings, were isolated from Alstonia scholaris. They promoted adult neuronal stem cells (NSCs) proliferation significantly,
in which the most active one (1) functioned from a concentration
of 0.1 μg/mL in a dosage-dependent manner. Furthermore, 1 enhanced NSC sphere formation and neurogenic fate commitment
through activation of a Wnt signaling pathway and promoted NSC differentiation
but did not affect proliferation of neuroblastoma cells.
创建时间：
2016-02-16
