IUGR is associated with an increased risk of obesity in offspring, which is likely driven in part by reprogramming of the hypothalamus due to suboptimal nutrition and hypoxia during development. As su
We have previously shown in sheep that 10 days of modest chronic increase in maternal cortisol result in fetal heart enlargement and Purkinje cell apoptosis. In subsequent studies in which we extended
In almost all animals, low physiological levels of oxygen (hypoxia) reduce growth rate and adult body size. Despite the near ubiquity of this response, the systemic mechanisms that coordinate growth
Includes data on tritiated steroids found in the three egg components over the course of egg development as well as TLC data in two different solvent systems.