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Chromatin position effects assayed by thousands of reporters integrated in parallel (cell lines with mPGK IRs)

ChEBI2013-08-16 更新2026-07-21 收录

染色质位置效应

高通量报告基因检测

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-49807 数据链接链接失效反馈

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资源简介：

Chromatin position effects assayed by thousands of reporters integrated in parallel (cell lines with mPGK IRs)

应用场景：

创建时间：

2013-08-16

转录因子功能验证

高通量报告基因检测

We performed a STARR-seq based, massively parallel reporter assay on reference genome and mutation-containing oligonucleotide sequences from regions associated with a large number of transcription fac

NIAID Data Ecosystem60

Use of NanoLuc-Based Reporters that Monitor Nonsense Suppression and Inhibition of Nonsense-Mediated mRNA Decay to Identify Potent New Agents That Partially Reverse the Effects of Nonsense Mutations

无义突变药物筛选

高通量报告基因检测

Premature termination codons (PTCs) lead to loss of protein function by 1) ending mRNA translation before a full-length protein is made, and 2) by triggering nonsense-mediated mRNA decay (NMD), a path

NIAID Data Ecosystem50

Chromatin position effects assayed by thousands of reporters integrated in parallel (mPGK TRIP pools). Mus musculus

染色质位置效应

报告基因分析

Reporter genes integrated into the genome are a powerful tool to reveal effects of regulatory elements and local chromatin context on gene expression. However, so far such reporter assays have been of

NIAID Data Ecosystem40

Sample input files for the pipeline described in "Best Practices for Massively Parallel Reporter Assays – Analyses, Diagnostics, and Interpretation"

功能基因组筛选

高通量报告基因检测

Version V6 for the input files

Zenodo2026-05-31 更新50

Chromatin position effects assayed by thousands of reporters integrated in parallel (mPGK TRIP pools)

染色质位置效应

多重报告基因检测

NIAID Data Ecosystem50