Adult lifespan of hyl-1;lagr-1 and N2 control worms subjected to empty vector control or the indicated RNAi at 20°C.

aMedian/mean RNAi lifespan of N2 and hyl-1;lagr-1 fed the specified RNAi-bacteria.bSome animals were censored as they crawled of the plate, ruptured, or died as a “bag of worms”, however they are incorporated in the data set up until the day they were censored. The number of individual trials is in parentheses.cMedian/mean control lifespan fed vector-only control bacteria.dP-values were determined using the Gehan-Breslow-Wilcoxon test using GraphPad Prism version 6.0 (GraphPad Software). The Bonferroni method was used to correct for multiple comparisons and P- values below 0.0125 are considered statistically significant equivalent to a significance level of 0.05 with four pair-wise comparisons. Cumulative statistics is shown in this table as experimental animals subjected to the same treatment behaved similarly between trials. Data shown in Figure 1.