five

Expression data from mouse optic nerve and optic tract

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE118804
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A membrane protein SIRPα (CD172a) interacts with another membrane protein CD47 and thereby constitutes a cell–cell contact signal. To investigate the functional role of CD47-SIRPα signal in the brain, we analyzed the effect of genetic ablation of CD47-SIRPα signal on the gene expression profile in specific brain regions by the use of microarrays. Total RNAs were prepared from the white matter (optic nerve and optic tract) of wild-type or CD47 knockout mice. Total RNAs from five (wild-type) and four (CD47 knockout) different genotype-matched animals were pooled and subjected to the analysis on Affymetrix Gene Chip.
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2019-07-10
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