The association of endosalpingiosis with malignancy

Endosalpingiosis is a poorly understood condition of ectopic epithelium resembling the fallopian tubes. It has been described as an incidental pathology finding, a disease similar to endometriosis, and in association with malignancy. We performed a retrospective analysis of 967 patients with endosalpingiosis (n=515) and endometriosis (n=452) over the span of 20 years at 3 affiliated academic hospitals to determine if there was an association with malignancy. The findings of our study was published in August 2022, and we have included the raw datasets here in order to share our data. The results of our data demonstrated that endosalpingiosis was found concurrently with malignancy in 40% of cases, and this effect was preserved in multi-variable and sub-group analyses.