Evolutionary characteristics of HIV-1 CRF51_01B isolates from Singapore and Malaysia.

aEstimated mean rates of evolution expressed as 10−3 nucleotide substitutions/site/year for the protease (subtype B), gp120 (CRF01_AE) and gp41 regions (subtype B) under a relaxed molecular clock with GTR+Γ4 substitution model and a constant size coalescent model. The 95% highest posterior density (HPD) confidence intervals are included in parentheses.bMean time of the most common ancestor (tMRCA, in calendar year) for protease (subtype B), gp120 (CRF01_AE) and gp41 (subtype B). The 95% HPD confidence intervals are indicated.cRefers to all CRF51_01B isolates from Singapore and Malaysia.dRefers to all CRF51_01B isolates from Singapore and Malaysia diverging from the ancestral strain 11MYKL055 who was a heterosexual.Evolutionary characteristics of HIV-1 CRF51_01B isolates from Singapore and Malaysia.