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资源简介：
R Dataset for Inflammation in ALS Data
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创建时间：
2024-03-27
相关数据集
ALS implicated protein TDP-43 sustains levels of STMN2 a mediator of motor neuron growth and repair. ALS implicated protein TDP-43 sustains levels of STMN2 a mediator of motor neuron growth and repair
The discovery that TDP-43 mutations cause familial ALS and that many patients display pathological TDP-43 mislocalization has nominated altered RNA metabolism as a potential disease mechanism. Despite
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Table_3_Early-life stress and dietary fatty acids impact the brain lipid/oxylipin profile into adulthood, basally and in response to LPS.xlsx
Brain lipid dysregulation is a hallmark of depression and Alzheimer’s disease, also marked by chronic inflammation. Early-life stress (ELS) and dietary intake of polyunsaturated fatty acids (PUFAs) ar
NIAID Data Ecosystem20
Effects of overexpression of GFP-TDP-43, GFP-TDP-43(86-414) or GFP in human H4 cells, in the presence or absence of the EIF2B activator DNL343.
Neuronal TDP-43 aggregates are a hallmark ALS pathology. The integrated stress response (ISR) occurs downstream of TDP-43 pathology and may exacerbate TDP-43 aggregation and neurodegeneration. Here we
NIAID Data Ecosystem00
Fig. 3d | TDP-43 localization and phosphorylation in ALS motor neurons
This item is part of the Figshare Project: Early mitochondrial dysfunction revealed across FUS- and TARDBP-ALS at single cell resolution From Data Availability Statement for the paper in Nature Comm
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Abnormal Changes in NKT Cells, the IGF-1 Axis, and Liver Pathology in an Animal Model of ALS
Amyotrophic lateral sclerosis (ALS) is a rapidly progressing fatal neurodegenerative disorder characterized by the selective death of motor neurons (MN) in the spinal cord, and is associated with loca
Figshare2016-01-18 更新10
