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Histone variant H2A.Z.2 mediates proliferation and drug sensitivity of malignant melanoma

ChEBI2015-07-01 更新2026-07-12 收录

黑色素瘤分子机制

肿瘤药物敏感性

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-59060 数据链接链接失效反馈

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资源简介：

Histone variant H2A.Z.2 mediates proliferation and drug sensitivity of malignant melanoma

应用场景：

创建时间：

2015-07-01

癌症生物标志物

肿瘤药物敏感性

Background: REV1 is a member of the translesion synthesis DNA polymerase Y family. It is an essential player in a variety of DNA replication activities, and perform major roles in the production of bo

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Significant GO terms for the top 300 genes that distinguish primary from cutaneous melanoma.

黑色素瘤分子机制

基因功能注释

Significant GO terms for the top 300 genes that distinguish primary from cutaneous melanoma.

NIAID Data Ecosystem70

Importance of RAD6B in activation of canonical WNT signaling in melanoma development

黑色素瘤分子机制

Wnt信号通路调控

We have demonstrated that RAD6B, a ubiquitin conjugating enzyme that is a principal component of translesion synthesis pathway, stabilizes and transcriptionally activates beta-catenin by lysine 63-lin

NIAID Data Ecosystem60

Establishment and Characterization of Primary Glioblastoma Cell Lines from Fresh and Frozen Material: A Detailed Comparison

胶质母细胞瘤模型

肿瘤药物敏感性

Background Development of clinically relevant tumor model systems for glioblastoma multiforme (GBM) is important for advancement of basic and translational biology. High molecular heterogeneity of GBM

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Epigenetic Regulation of KPC1 Ubiquitin Ligase Affects the NF-?B Pathway in Melanoma

黑色素瘤分子机制

NF-κB通路调控

Melanoma is a highly aggressive cancer with increasing incidence rates and a poor survival, particularly in patients with AJCC stage IV and advanced stage III. Deregulation of NF-kB is linked to diffe

NIAID Data Ecosystem70

Histone variant H2A.Z.2 mediates proliferation and drug sensitivity of malignant melanoma

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