Crystal Structure of SETDB1 Tudor domain in complexed with (R,R)-59
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Crystal Structure of SETDB1 Tudor domain in complexed with (R,R)-59 Descriptor: 2-[[(3~{R},5~{R})-1-methyl-5-(4-phenylmethoxyphenyl)piperidin-3-yl]amino]-3-prop-2-enyl-5~{H}-pyrrolo[3,2-d]pyrimidin-4-one, Histone-lysine N-methyltransferase SETDB1 Authors: Guo, Y.P, Liang, X, Mao, X, Wu, C, Luyi, H, Yang, S. Deposit date: 2020-07-13 Release date: 2021-04-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.474 Å) Cite: Structure-Guided Discovery of a Potent and Selective Cell-Active Inhibitor of SETDB1 Tudor Domain. Angew.Chem.Int.Ed.Engl., 60, 2021
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2020-07-13
