Structure of cyclodipeptide synthase from Nocardia brasiliensis (Nbra-CDPS) in complex with alanylated RNA microhelices analogues mimicking Ala-tRNA-Ala substrate

Structure of cyclodipeptide synthase from Nocardia brasiliensis (Nbra-CDPS) in complex with alanylated RNA microhelices analogues mimicking Ala-tRNA-Ala substrate Descriptor: Cyclodipeptide synthase, RNA (5'-R(P*GP*GP*GP*GP*CP*UP*AP*UP*UP*CP*GP*UP*AP*GP*CP*UP*CP*CP*AP*CP*C)-3') Authors: Marouf, Z, Charbonnier, J.B, Fernandez Varela, P, Legrand, P. Deposit date: 2025-02-11 Release date: 2026-03-11 Last modified: 2026-04-22 Method: X-RAY DIFFRACTION (3.61 Å) Cite: The tRNA moieties of both aminoacyl-tRNA substrates of a cyclodipeptide synthase share a common binding site, as revealed by RNA microhelices mimicking tRNA acceptor arms. Nucleic Acids Res., 54, 2026