hBD2 in Murine Cigarette Smoke Exposure. hBD2 in Murine Cigarette Smoke Exposure

Cigarette smoke exposure induces pulmonary inflammation despite increased risk of lung infection. We tested the ability of human beta-defensin 2, an antimicrobial peptide, to modulate inflammatory processes while promoting immune competence. Overall design: n=4-5 per group, 4 groups, RA-Veh = room air-exposed vehicle-treated, RA-hBD2 = room air-exposed hBD2-treated, CS-PBS = cigarette smoke-exposed vehicle-treated, and CS-hBD2 = cigarette smoke-exposed hBD2-treated