Differential effects of m6A modification and YTHDF2 knockdown on global mRNA turnover
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https://www.ncbi.nlm.nih.gov/sra/SRP331939
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资源简介：
We developed a method to deconvolute decays of m6A mRNAs and their unmethylated isoforms from total RNAs across the transcriptome and combined it with the knockdown of m6A reader protein to study it's effect on global mRNA turnover. Overall design: M6A-RIP-seq approach was combined with time-course experiments to monitor m6A mRNA and unmethylated isoform mRNA decays across the transcriptome upon DF2 knockdown. Knockdown with a negtaive control siRNA was used as a control. Fifty-four samples of total cytoplasmic RNA were generated.
创建时间：
2025-02-03
