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Crystal structure of a genotype 1a/3a chimeric HCV NS3/4A protease in complex with Vaniprevir

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Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
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Crystal structure of a genotype 1a/3a chimeric HCV NS3/4A protease in complex with Vaniprevir Descriptor: (5R,7S,10S)-10-tert-butyl-N-{(1R,2R)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethylcyclopropyl}-15,15-dimethyl-3,9,12-trioxo-6,7,9,10,11,12,14,15,16,17,18,19-dodecahydro-1H,5H-2,23:5,8-dimethano-4,13,2,8,11-benzodioxatriazacyclohenicosine-7(3H)-carboxamide, NS3 protease, SULFATE ION, ... Authors: Soumana, D, Yilmaz, N.K, Ali, A, Prachanronarong, K.L, Schiffer, C.A. Deposit date: 2015-11-16 Release date: 2016-11-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Molecular and Dynamic Mechanism Underlying Drug Resistance in Genotype 3 Hepatitis C NS3/4A Protease. J.Am.Chem.Soc., 138, 2016
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2015-11-16
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