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The Tec kinase ITK optimizes differential NFAT, NF-κB, and Erk1/2 signaling to regulate graded gene induction in mouse CD8+ T cells [ATAC-seq]

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NIAID Data Ecosystem2026-03-12 收录
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In this study we generated ATAC-seq libraries from mouse CD8+ OT-I T cells that were stimulated with WT splenocytes loaded with OVA peptide or OVA peptide variants, with or without presence of ITK inhibitor PRN-694 at early time points (0, 30min, 60min, or 120min). ATAC-seq data of peptide-stimulated OT-I T cells at early time points.

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2021-02-24
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